Dr. med. Patrick House, epileptologist and board-certified neurologist

Epilepticon – Who we are

About us

To ensure the best possible outpatient care for patients, Dr. Patrick House and theBlue.ai have joined forces in a cooperation and built Epilepticon together. With the expertise of Dr. Patrick House and the technology of theBlue.ai, Epilepticon combines the right competencies to strengthen patient autonomy and significantly improve outpatient care for people with epilepsy.

Dr. med. Patrick House, epileptologist and board-certified neurologist

Dr. med. Patrick House

Epileptologist and board-certified neurologist

  • Epileptologist for 20 years
  • 15 years as senior physician at the Epilepsy Center Hamburg (2007 – 2022)
  • Since 2022: Epileptologicum Hamburg, a practice specializing in epileptology
  • Since 2017: cooperation with the Hamburg start-ups theBlue.ai and apoQlar
  • Since 2021: founding member of the HoloMedicine Association
  • Since September 2022: Chief Medical Officer (CMO) at theBlue.ai
  • Specialization in high-resolution, epilepsy-optimized MRI imaging and the detection of epileptogenic focal cortical dysplasias (FCDs) – small epileptogenic brain lesions that are often overlooked by radiologists and neuroradiologists
  • 15 years of experience with high-resolution MRI post-processing (8,000 MRIs, 900 FCDs detected)

Publications

Digital MRI post-processing with/without artificial intelligence (AI) for the detection of focal cortical dysplasias (FCD)

  • House PM, Kopelyan M, Braniewska N, Silski B, Chudzinska A, Holst B, Sauvigny T, Martens T, Stodieck S, Pelzl S (2021): “Automated detection and segmentation of focal cortical dysplasias (FCDs) with artificial intelligence: Presentation of a novel convolutional neural network and its prospective clinical validation”. Epilepsy Research 172(6):106594
  • House PM, Holst B, Lindenau M, Voges B, Kohl B, Martens T, Lanz M, Stodieck S, Huppertz HJ (2015): “Morphometric MRI analysis enhances visualization of cortical tubers in tuberous sclerosis”. Epilepsy Research 117, 39-43
  • House PM, Holst B, Martens T, Kohl B, Voges B, Lindenau M, Lanz M, Osseforth J, Stodieck SRG, Huppertz HJ (2014): “Morphometric MRI analysis enhances visualization of cortical tubers in tuberous sclerosis”. Poster: European Congress on Epileptology 2014 in Stockholm, Sweden
  • Lanz M, Martens T, Lindenau M, Voges B, Stodieck S, House P (2013): „MRT Postprocessing bei Patienten mit hypermotorischen Anfällen – eine Fallserie“. Poster: Dreiländertagung 2013 in Interlaken, Switzerland
  • House PM, Lanz M, Holst B, Martens T, Stodieck S, Huppertz HJ (2013): “Comparison of morphometric analysis based on T1- and T2-weighted MRI data for visualization of focal cortical dysplasia”. Epilepsy Research 106, 403-409
  • House PM, Lanz M, Holst B, Martens T, Stodieck S, Huppertz HJ (2013): „Vergleich morphometrischer Analysen von T1- und T2-gewichteten 3D-MRT-Datensätzen zur Visualisierung fokaler kortikaler Dysplasien“. Poster (Poster Award Winner): Dreiländertagung 2013 in Interlaken, Switzerland
  • Huppertz HJ, Wagner J, Weber B, House P, Urbach H (2011): “Automated quantitative FLAIR analysis in hippocampal sclerosis”. Epilepsy Research 97, 146-156

Functional transcranial Doppler sonography (fTCD)

  • House PM, Brückner KE, Lohmann HH (2011): “Presurgical functional transcranial Doppler sonography (fTCD) with intravenous echo enhancing agent SonoVue enables determination of language lateralization in epilepsy patients with poor temporal bone windows”. Epilepsia 52 (3), 636-639
  • House PM, Brückner KE, Wendtland F, Stodieck S (2011): „Echokontrastverstärkte fTCD zur Sprachdominanzbestimmung im Rahmen der prächirurgischen Epilepsiediagnostik bei Patienten mit insuffizienten transtemporalen Schallfenstern“. Poster: Dreiländertagung 2011 in Graz, Austria

Deep brain stimulation (DBS)

  • House PM, Herzer A, Lorenzi I, Niedernhöfer P, Voges B, Stodieck S, Westphal M, Schaper M, Koeppen JA, Hamel W (2021): “Deep brain stimulation (DBS) of anterior nucleus thalami (ANT) in female epilepsy patients during pregnancy and delivery: experience from two cases”. Epileptic Disorders, doi: 10.1684/epd.2021.1330
  • Koeppen JA, Nahravani F, Kramer M, Voges B, House PM, Gulberti A, Moll CKE, Westphal M, Hamel W (2018): “Electrical Stimulation of the Anterior Thalamus for Epilepsy: Clinical Outcome and Analysis of Efficient Target”. Neuromodulation, doi: 10.1111/ner.12865
  • Voges BR, Schmitt FC, Hamel W, House PM, Kluge C, Moll CKE, Stodieck SR (2015): “Deep brain stimulation of anterior nucleus thalami disrupts sleep in epilepsy patients”. Epilepsia, doi: 10.1111/epi.13045
  • Köppen JA, Voges B, House PM, Nahravani F, Huckhagel T, Engel AK, Westphal M, Stodieck S, Kuhlmann C, Gulberti A, Moll CKE, Hamel W (2014): “Anterior nucleus of the thalamus (ANT) stimulation in epilepsy: stereotactic targeting and localization of effective contacts”. Conference Paper: Congress of the European Society for Stereotactic and Functional Neurosurgery 2014 in Maastricht, Netherlands
  • Voges B, Hamel W, House PM, Lanz M, Stodieck SRG (2013): “Effect of Deep Brain Stimulation of the Anterior Nucleus of Thalamus on quality and structure of sleep in patients with epilepsy”. Poster: International Epilepsy Congress 2013 in Montreal, Canada

3D visualization, neuronavigation and patient education

  • House PM, Pelzl S, Furrer S, Lanz M, Simova O, Voges B, Stodieck SRG, Brückner KE (2019): “Use of the mixed reality tool ‘VSI Patient Education’ for more comprehensible and imaginable patient educations before epilepsy surgery and stereotactic implantation of DBS or stereo-EEG electrodes”. Epilepsy Research, doi: 10.1016/j.eplepsyres.2019.106247
  • House PM, Pelzl S, Furrer S, Simova O, Voges B, Stodieck SRG, Brückner KE (2019): „VSI Patient Education für Aufklärungen vor epilepsiechirurgischen Operationen“. Poster: Dreiländertagung 2019 in Basel, Switzerland

Other epileptological and neurological topics

  • Adan G, Gerdes JS, De Bezenac C, House PM, Stodieck S, Keller SS (2022): “Changes in Imaging defined BrainAGE following a first seizure”. Conference Paper: AES Annual Meeting 2021
  • Leek N, Gerdes JS, De Bezenac C, House PM, Stodieck S, Keller SS (2022): “Morphometric similarity network alterations in patients presenting with a first seizure”. Conference Paper: AES Annual Meeting 2021
  • Taherpour J, Jaber M, Voges BR, Apostolova I, Sauvigny T, House PM, Lanz M, Lindenau M, Klutmann S, Martens T, Stodieck S, Buchert R (2021): “Predicting the Outcome of Epilepsy Surgery by Covariance Pattern Analysis of Ictal Perfusion SPECT”. Journal of Nuclear Medicine 63(6):jnumed.121.262702, doi: 10.2967/jnumed.121.262702
  • Jaber M, Taherpour J, Voges BR, Apostolova I, Sauvigny T, House PM, Lanz M, Lindenau M, Klutmann S, Martens T, Stodieck S, Buchert R (2021): “No Evidence to Favor 99mTc-HMPAO or 99mTc-ECD for Ictal Brain Perfusion SPECT for Identification of the Seizure Onset Zone”. Clinical Nuclear Medicine 2021 Nov 1;46(11):890-895
  • Trabs N, Trabs M, Stodieck S, House PM (2020): “Influence of stiripentol on perampanel serum levels”. Epilepsy Research, doi: 10.1016/j.eplepsyres.2020.106367
  • Rave F, Hebel JM, House PM, Lorenzi I, Buchert R, Hamel W, Koeppen JA, Martens T, Stodieck SRG, Lanz M (2019): „Co-Registrierung prächirurgischer Bildbefunde mit invasiv erhobenen sEEG-Daten“. Conference Paper: Dreiländertagung in Basel, Switzerland
  • Voges BR, Schmitt FC, House PM, Stodieck SR, Schenck CH (2018): “Complex sexual behaviors during sleep as a manifestation of epilepsy: A case series”. Sleep, doi: 10.1093/sleep/zsy233
  • Dührsen L, Sauvigny T, House PM, Stodieck S, Holst B, Matschke J, Schön G, Westphal M, Martens T (2017): “Impact of focal cortical dysplasia Type IIIa on seizure outcome following anterior mesial temporal lobe resection for the treatment of epilepsy”. J Neurosurg, doi: 10.3171/2017.2.JNS161295
  • House PM, Stodieck SRG (2016): “Octreotide: The IIH therapy beyond weight loss, carbonic anhydrase inhibitors, lumbar punctures and surgical/interventional treatments”. Clinical Neurology and Neurosurgery 150, 181-184
  • House PM (2015): „Therapie epileptischer Anfälle bei Patienten mit Hirntumoren“. TumorDiagnostik & Therapie 36 (1), 22-25
  • Dührsen L, Matschke J, House P, Stodieck S, Westphal M, Martens T (2015): “Impact of focal cortical dysplasia type IIIa on seizure outcome following anterior mesial temporal lobe resection for treatment in epilepsy”. Conference Paper: Dreiländertagung in Dresden, Germany
  • Böcker S, House P, Lindenau M, Martens T, Voges B, Stodieck S, Lanz M (2014): „Lokalisatorische Bedeutung von Semiologie und Oberflächen-EEG bei Frontallappenepilepsien in Folge einer fokalen cortikalen Dysplasie (FCD)“. Poster: Jahrestagung der Deutschen Gesellschaft für Epileptologie 2014 in Bonn, Germany
  • Heimes J, Stodieck S, Voges B, House P, Lindenau M, Lanz M (2012): „Steroidresponsiver PLEDs-assoziierter Status aphasicus – Ein Fallbericht“. Poster: DGN 2012 in Hamburg, Germany

Interests and areas of focus

  • Visualization, neuronavigation, patient education and teaching using 3D mixed/augmented reality
  • Automated FCD detection with artificial intelligence (AI)
  • Automated seizure detection with artificial intelligence (AI)

Would you like to learn more about Epilepticon? Contact us.

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